🧠 Virtual Presentation Spotlight – Cancer Conference 2025
📅 November 17–19,
2025 | 📍 Village Hotel
Changi, Singapore & Online
🌐 Event
Website
We are delighted to welcome Prof. Janusz Rak, MD, PhD, McGill
University, Canada, as a distinguished Oral Virtual Presenter at the
Cancer Conference 2025. Prof. Rak is a world-leading expert in pediatric
hematology/oncology, renowned for his pioneering research into how cancer cells
communicate with their environment via extracellular vesicles (EVs).
Presentation Title:
Extracellular vesicle pathways as regulators of tumor-vascular interactionsin glioblastoma
Glioblastoma (GBM) remains one of the most aggressive and lethal brain
tumors, resisting conventional therapies despite decades of study. Prof. Rak’s
groundbreaking work sheds new light on the critical role of extracellular
vesicles in orchestrating communication between glioma stem cells (GSCs)
and the vascular system—driving processes like angiogenesis, vasectasia, and
immune cell access to tumor tissue.
His team has uncovered that GSC subtypes secrete unique repertoires of
EVs, influencing vascular growth patterns in GBM. Of particular interest is
their discovery of a VEGF-independent blood vessel enlargement process—vasectasia—triggered
by EV-mediated transfer of oncogenic EGFRvIII to endothelial cells, which
resists standard angiogenesis inhibitors. Moreover, endothelial-derived EVs can
reprogram proneural GSCs into more invasive, therapy-resistant mesenchymal
phenotypes. These insights reveal new therapeutic possibilities, including
combining vascular modulation with immunotherapy to improve treatment outcomes.
About the Speaker:
Prof. Janusz Rak is a Professor of Pediatrics and Jack Cole Chair in
Pediatric Hematology/Oncology at McGill University. He directs the Centre
for Applied Nanomedicine (CAN) and leads innovative projects on EV-based
liquid biopsy approaches in pediatric cancer. He is also a Fellow of the Royal
Society of Canada, recognized for his exceptional contributions to cancer
biology.
📞 Contact Us
📧 Email:
cancer@mathewsconference.com
📱 WhatsApp: +1 (424)
377 0967
📞 Phone: +1 (312)
462-4448
#Glioblastoma
#BrainCancerResearch #CancerConference #LiquidBiopsy #OncologyResearch
#VirtualConference #MedicalResearch #Cancer2025